Denosumab cessation
نویسندگان
چکیده
منابع مشابه
Denosumab (Prolia) Injection
Vol. 35 No. 10 • October 2010 • P&T® 553 INTRODUCTION A healthy skeleton is essential for providing structural support, protection of vital organs and the hematopoietic system, and maintenance of homeostasis of calcium and other ions. Skeletal bone (composed of trabecular and cortical bone) is a dynamic tissue that constantly undergoes remodeling in response to mechanical stresses and hormonal ...
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The legal basis for this application refers to Article 8.3 of Directive 2001/83/EC, as amended-complete and independent application The application submitted is a complete dossier composed of administrative information, complete quality data, non-clinical and clinical data based on applicants' own tests and studies and/or bibliographic literature substituting/supporting certain tests or studies...
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Correspondence: Robert A Adler McGuire veterans Affairs Medical Center, 1201 Broad Rock Boulevard, Richmond, vA 23249, USA Tel +1 804 675 5424 Fax +1 804 675 5425 email [email protected] Abstract: While most older patients with osteoporosis are treated with antiresorptive bisphosphonates such as alendronate, risedronate, ibandronate, and zoledronic acid, such drugs have side effects, remain i...
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Open Access This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. DOI 10.3109/17453674.2013.859423 Stress fractures of the femoral shaft or subtrochanteric region (atypical femoral fractures) are clearly associated with bisphosphonat...
متن کاملDenosumab treatment for fibrous dysplasia.
Fibrous dysplasia (FD) is a skeletal disease caused by somatic activating mutations of the cyclic adenosine monophosphate (cAMP)-regulating protein, α-subunit of the Gs stimulatory protein (G(s) α). These mutations lead to replacement of normal bone by proliferative osteogenic precursors, resulting in deformity, fracture, and pain. Medical treatment has been ineffective in altering the disease ...
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ژورنال
عنوان ژورنال: Cleveland Clinic Journal of Medicine
سال: 2020
ISSN: 0891-1150,1939-2869
DOI: 10.3949/ccjm.87a.20040